Plague Inc: Evolved

Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected ‘Patient Zero’ – now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.

Plague Inc. is so realistic that the CDC even asked the developer to come and speak about the infection models in the game!
http://blogs.cdc.gov/publichealthmatters/2013/04/plague-inc/
Over 100 million players have been infected by Plague Inc. already. Now, Plague Inc: Evolved combines the original critically acclaimed gameplay with significant, all-new features for PC including multiplayer, user-generated content support, improved graphics and lots more.
10 Different Disease Types – Master every pathogen; from bacteria to bio-weapons and mind control to zombies, end humanity by any means possible – different diseases will need radically different approaches.

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System Requirement

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Minimum:

• OS: Windows 8
• Processor: 2.0 GHz Dual Core Processor
• Memory: 1 GB RAM
• Graphics: Integrated Graphics (512MB)
• Storage: 500 MB available space
• Additional Notes: Unsupported video chipsets: Intel HD Graphics 3000, Intel GMA X3100, Intel GMA 950

Recommended:

• OS: Windows 10
• Processor: 3.0GHz i5 Dual Core or equivalent
• Memory: 2 GB RAM
• Graphics: Nvidia GeForce GTX 650 Radeon HD 3600 (1GB)
• Storage: 1 GB available space
• Additional Notes: Unsupported video chipsets: Intel HD Graphics 3000, Intel GMA X3100, Intel GMA 950